The theme of “Extremophiles and Extremozymes: From Life at the Limits to a Sustainable Bioeconomy” reflects both the diversity of extremophilic life and its growing impact on science and society. By exploring how organisms thrive under the most challenging conditions on Earth, we gain profound insights into evolution, adaptation, and survival. At the same time, the unique enzymes and biomolecules derived from these organisms provide powerful tools for industrial innovation and sustainability. This congress will bridge fundamental discoveries with translational applications, highlighting the role of extremophiles and extremozymes in building a future-oriented bioeconomy.